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These measures indicate that males with CAH are exposed to greater prenatal concentrations of total androgens than are control males.Digit ratio in men with Klinefelter's syndrome, who have reduced testosterone secretion throughout life compared to control males, are greater (i.e., more feminine) than in their fathers or control males.

The 2D:4D ratio is calculated by dividing the length of the index finger of a given hand by the length of the ring finger of the same hand.

A longer index finger will result in a ratio higher than 1, while a longer ring finger will result in a ratio lower than 1.

Since the publication of Lopata's classic work, however, few studies have explored empirically the ways that widow(er)'s dating affects their relationships with children.

We use prospective data from the Changing Lives of Older Couples study (CLOC) to explore: (1) the impact of bereaved spouses' dating on positive and negative aspects of parent–child relationships six and 18 months postloss; (2) the extent to which these associations are explained by preloss characteristics; and (3) the factors that moderate the association between widow(er) dating and parent–child relations.

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During this period if the fetus is exposed to androgens, the exact level of which is thought to be sexually dimorphic, the growth rate of the 4th digit is increased, as can be seen by analyzing the 2D:4D ratio of opposite sex dizygotic twins, where the female twin is exposed to excess androgens from her brother in utero, and thus has a significantly lower 2D:4D ratio.

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