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But SSRIs can have serious side effects and don’t work for everyone, possibly up to 40 percent of those who try them (1).Some research shows they work no better than a placebo (2).If this is your situation, here are some serotonin supplements proven to help increase serotonin levels naturally.

It’s believed that low serotonin is the underlying cause of depression.

Selective serotonin reuptake inhibitors (SSRIs) such as Paxil, Prozac, Zoloft, Celexa, and Lexapro are used by millions to relieve symptoms of depression by increasing brain levels of serotonin.

But since protein blocks serotonin synthesis, eating a meal containing protein will actually cause both tryptophan and serotonin levels drop.

However, tryptophan supplements can increase brain serotonin even though eating foods containing tryptophan does not (5).

Serotonin supplements like specific amino acids, vitamins, minerals and herbs increase serotonin levels helping depression and other brain-related disorders.

Serotonin is a neurotransmitter that plays a large role in mood, learning, appetite control, and sleep.5-HTP (5-hydroxytryptophan): 5-HTP could be considered as either an amino acid or herbal supplement.It comes from Griffonia simplicifolia, an African woody shrub. But we’ve put it in the amino acid category since it’s so closely associated with tryptophan. S., Canada, and the United Kingdom, 5-HTP is sold as an over-the-counter supplement for ADHD, anxiety, depression, fibromyalgia, migraines, sleep disorders, and weight loss (7).Within a few months, this inevitably causes a cascade of negative side effects (10). Datis Kharrazian, author of , lists these co-factors as needed for the synthesis of either tryptophan or 5-HTP to serotonin — vitamins B3, B6, and B12, folic acid, and magnesium.Look either for serotonin boosting supplements that contain these along with the main active ingredients or add them separately with a high-quality multivitamin mineral supplement.Several other brain-related disorders besides depression are related to low serotonin, including autism, ADHD, bipolar disorder, sleep disorders, and schizophrenia (3).

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