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Some users may experience an episode of acute psychosis, which usually abates after six hours, but in rare instances, heavy users may find the symptoms continuing for many days.
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Cannabis is believed to be an aggravating factor in rare cases of arteritis, a serious condition that in some cases leads to amputation.
Because 97% of case-reports also smoked tobacco, a formal association with cannabis could not be made.
In 2008-9 some 651 admissions were recorded by the NHS in England relating to a diagnosis of ‘mental or behavioural disorder due to use of cannabinoids’.
By 2011-12, that figure had risen to more than 1000.‘I think that too often, people are willing to romanticise cannabis.
Addiction experts in psychiatry, chemistry, pharmacology, forensic science, epidemiology, and the police and legal services engaged in delphic analysis regarding 20 popular recreational drugs.
Cannabis was ranked 11th in dependence, 17th in physical harm, and 10th in social harm.
Research in these events is complicated because cannabis is often used in conjunction with tobacco, and drugs such as alcohol and cocaine.
These putative effects can be taken in context of a wide range of cardiovascular phenomena regulated by the endocannabinoid system and an overall role of cannabis in causing decreased peripheral resistance and increased cardiac output, which potentially could pose a threat to those with cardiovascular disease.
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